Invention Grant
- Patent Title: Universal molecular processor for precision medicine
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Application No.: US15560028Application Date: 2016-03-23
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Publication No.: US10393726B2Publication Date: 2019-08-27
- Inventor: Steven A. Soper , Francis Barany , Sunggook Park , Michael Murphy , Collin J. McKinney , John William Efcavitch , Mateusz Hupert
- Applicant: The University of North Carolina at Chapel Hill , Cornell University , Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
- Applicant Address: US NC Chapel Hill US NY Ithaca US LA Baton Rouge
- Assignee: The University of North Carolina at Chapel Hill,Cornell University,Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
- Current Assignee: The University of North Carolina at Chapel Hill,Cornell University,Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
- Current Assignee Address: US NC Chapel Hill US NY Ithaca US LA Baton Rouge
- Agency: Myers Bigel, P.A.
- International Application: PCT/US2016/023769 WO 20160323
- International Announcement: WO2016/154302 WO 20160929
- Main IPC: G01N33/487
- IPC: G01N33/487 ; C12M1/40 ; B01L3/00 ; C12M3/06 ; C12Q1/6806 ; C12Q1/6869 ; C12Q1/6837 ; C12Q1/6874

Abstract:
The present invention is directed to a device that comprises a biomolecular processor and one or more nanotubes. Each biomolecular processor comprises a bioreactor chamber defined by a solid substrate, a plurality of spaced support structures within said bioreactor chamber and attached to the solid substrate, and one or more capture molecules immobilized to some or all of said plurality of spaced support structures, said one or more capture molecules suitable to bind to a portion of a target nucleic acid molecule in a sample. The device also comprises one or more nanotubes defined by the solid substrate and fluidically coupled to the bioreactor chamber.
Public/Granted literature
- US20180074039A1 UNIVERSAL MOLECULAR PROCESSOR FOR PRECISION MEDICINE Public/Granted day:2018-03-15
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