The present disclosure relates to method and system of implementing one wire programmable circuit by using the same terminal OUT as both main circuit output terminal and the digital I/O interfacing terminal of the circuit. The present invention overcomes the shortcoming of prior arts and does not require the circuit to be powered down first and then powered up again each time the circuit is switched between interfacing mode (read/write/program OTP) and the normal output mode, therefore shorten the time of interfacing with the OTP as well as simplified the interfacing system used to read/write/program the OTP. The present invention also enables the possibility to put the no longer required system clock into sleeping mode after the OTP has been programmed, and has the advantages of reducing system power consumption as well as system noise due to the existing of digital clock.