A decompression panel assembly for use in an aircraft includes a frame including a first surface and an opposing second surface, wherein the frame defines a grille opening and at least partially defines a flow path opening. The decompression panel assembly also includes a face panel having a first surface retained against the frame second surface such that the face panel at least partially covers the grille opening. A retention mechanism is coupled to the face panel and is configured to retain the face panel against the frame in a closed position.