Invention Grant
- Patent Title: Substituted pyrrolidines and methods of use
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Application No.: US15723896Application Date: 2017-10-03
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Publication No.: US10399940B2Publication Date: 2019-09-03
- Inventor: Robert J. Altenbach , Andrew Bogdan , Nicolas Desroy , Gregory A. Gfesser , Stephen N. Greszler , John R. Koenig , Philip R. Kym , Bo Liu , Marc J. Scanio , Xenia Searle , Xueqing Wang , Ming C. Yeung , Gang Zhao
- Applicant: AbbVie S.à.r.l. , Galapagos NV
- Applicant Address: LU Luxembourg BE Mechelen
- Assignee: AbbVie S.á.r.l.,Galapagos NV
- Current Assignee: AbbVie S.á.r.l.,Galapagos NV
- Current Assignee Address: LU Luxembourg BE Mechelen
- Agency: Quarles & Brady LLP
- Main IPC: C07D401/12
- IPC: C07D401/12 ; C07D401/14 ; C07D207/16 ; A61K31/40 ; A61K31/4439 ; A61K31/4709 ; A61K31/506 ; A61K45/06 ; C07D403/12 ; C07D405/14
Abstract:
The invention discloses compounds of Formula (I) wherein R1, R2, R2A, R3, R3A, R4, and R5 are as defined herein. The present invention relates to compounds and their use in the treatment of cystic fibrosis, methods for their production, pharmaceutical compositions comprising the same, and methods of treating cystic fibrosis by administering a compound of the invention.
Public/Granted literature
- US20180099932A1 Substituted Pyrrolidines and Methods of Use Public/Granted day:2018-04-12
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