- Patent Title: Negative allosteric modulators of metabotropic glutamate receptor 3
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Application No.: US15549944Application Date: 2016-02-10
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Publication No.: US10399948B2Publication Date: 2019-09-03
- Inventor: P. Jeffrey Conn , Craig W. Lindsley , Kyle A. Emmitte , Julie L. Engers , Katrina A. Bollinger , Megan M. Breiner
- Applicant: Vanderbilt University
- Applicant Address: US TN Nashville
- Assignee: Vanderbilt University
- Current Assignee: Vanderbilt University
- Current Assignee Address: US TN Nashville
- Agency: Michael Best & Friedrich LLP
- International Application: PCT/US2016/017318 WO 20160210
- International Announcement: WO2016/130652 WO 20160818
- Main IPC: C07D213/04
- IPC: C07D213/04 ; C07D213/69 ; C07D401/04 ; C07D401/12 ; A61K31/444 ; A61K31/435 ; C07D239/60 ; C07D237/16 ; C07D239/52
Abstract:
Described are negative allosteric modulators of metabotropic glutamate receptor 3 (mGlu3), pharmaceutical compositions including the compounds, and methods of using the compounds and compositions for treating depression, cognitive disorders, schizophrenia, Alzheimer's disease, or cancer in a subject.
Public/Granted literature
- US20180022712A1 NEGATIVE ALLOSTERIC MODULATORS OF METABOTROPIC GLUTAMATE RECEPTOR 3 Public/Granted day:2018-01-25
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