Invention Grant
- Patent Title: PPAR agonists, compounds, pharmaceutical compositions, and methods of use thereof
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Application No.: US15766455Application Date: 2016-10-05
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Publication No.: US10399958B2Publication Date: 2019-09-03
- Inventor: Michael Downes , Ronald M. Evans , Arthur Kluge , Bharat Lagu , Masanori Miura , Sunil Kumar Panigrahi , Michael Patane , Susanta Samajdar , Ramesh Senaiar , Taisuke Takahashi
- Applicant: Mitobridge, Inc. , The Salk Institute for Biological Studies
- Applicant Address: US MA Cambridge US CA La Jolla
- Assignee: Mitobridge, Inc.,The Salk Institute for Biological Studies
- Current Assignee: Mitobridge, Inc.,The Salk Institute for Biological Studies
- Current Assignee Address: US MA Cambridge US CA La Jolla
- Agency: McCarter & English, LLP
- Agent Steven G. Davis; Wei Song
- International Application: PCT/US2016/055521 WO 20161005
- International Announcement: WO2017/062468 WO 20170413
- Main IPC: C07D233/64
- IPC: C07D233/64 ; C07D401/04 ; C07D405/10 ; A61P21/00 ; A61P25/00
Abstract:
Provided herein are compounds I, II or III and compositions useful in increasing PPAR8 activity. The compounds and compositions provided herein are useful for the treatment of PPAR8 related diseases (e.g., muscular diseases, vascular disease, demyelinating disease, and metabolic diseases).
Public/Granted literature
- US20190084958A1 PPAR AGONISTS, COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF Public/Granted day:2019-03-21
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