- Patent Title: Polylactide and apatite compositions and methods of making the same
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Application No.: US14391044Application Date: 2013-03-08
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Publication No.: US10400083B2Publication Date: 2019-09-03
- Inventor: Tongxin Wang , James W. Mitchell
- Applicant: Tongxin Wang , James W. Mitchell
- Applicant Address: US DC Washington
- Assignee: Howard University
- Current Assignee: Howard University
- Current Assignee Address: US DC Washington
- Agency: Fitch, Even, Tabin & Flannery, LLP
- International Application: PCT/US2013/029839 WO 20130308
- International Announcement: WO2013/154704 WO 20131017
- Main IPC: C08K3/32
- IPC: C08K3/32 ; A61L27/12 ; A61L27/18 ; A61L27/58
Abstract:
A method is provided for synthesizing PLA/apatite composites with improved mechanical strength. In one aspect, a calcium-phosphate/phosphonate hybrid shell is developed to incorporate more reactive hydroxyl groups onto hydroxyapatite (HA) particles. PLA is covalently bonded to HA calcium phosphate hybrid shell, creating a strong interphase between HA and PLA, thus significantly improve the mechanical strength in comparison to that of non-modified HA.
Public/Granted literature
- US20150065632A1 Polylactide And Apatite Compositions And Methods Of Making The Same Public/Granted day:2015-03-05
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