In some aspects, a compressor system includes a compressor train including two or more compressors connected in series and a control mechanism. The control mechanism is controlled by a performance controller. The performance controller is operable to identify a process variable of the performance controller; receive, on a recurrent basis from a load sharing controller, a setpoint for the process variable of the performance controller; and control the control mechanism based on the setpoint and the process variable of the performance controller. The setpoint is determined dynamically during operation of the two or more compressors by the load sharing controller based on a load sharing parameter associated with the two or more compressors.