A novel six-dimensional force and torque sensor includes a central boss, a cylindrical housing arranged outside the central boss, and twelve elastic beams for connecting the central boss with the cylindrical housing. The twelve elastic beams are respectively provided with strain gauges as needed, and a bottom of the central boss is provided with a mounting hole for mounting a signal processing module. The present invention has the characteristics of self-decoupling, high rigidity, high natural frequency, desirable linearity, ideal repeatability and perfect hysteresis, and ability to measure a large torque (50 N·m). In addition, the sensor can be designed to have different measuring ranges and sensitivities by changing the dimensions of each of the elastic beams.