A system is provided for manufacturing a component within a factory. The system may have an autonomous vehicle configured to transport the component to an area within an open space of the factory and to secure the component at the area during processing of a designated volume of the component. The system may also have a plurality of processing modules each configured to process a portion of the component less than a whole of the designated volume, and a controller in communication with the autonomous vehicle and the plurality of processing modules. The controller may be configured to coordinate operations of the plurality of processing modules according to a programmed process plan.