An intelligent sensing touch display device capable of being responsive to an application program to selectively perform a touch detection procedure on a first electrode group and/or on an active array unit, where a controller has a memory for storing background image data, and data of at least one object image, and is used for performing a local operation procedure including steps of: receiving location information of at least one touched GUI object provided by a touch and display driving unit and transmitting the location information to a main processing unit; receiving updated image data for at least one GUI object image from the main processing unit; combining the updated image data with the background image data to form locally updated display image data and transmitting the locally updated display image data to the touch and display driving unit.