A Network Function Virtualization (NFV) data communication system implements hardware trusted Management and Orchestration (MANO). A Hardware (HW) trust server issues a HW trust challenge to a MANO system. The MANO system hashes its physically-embedded hardware trust key to generate a HW trust result and transfers the HW trust result to the HW trust server. The HW trust server validates the hardware trust result and transfers a HW trust certificate to the MANO system. The MANO system transfers the HW trust certificate and NFV MANO data to an NFV Infrastructure (NFVI). The NFVI validates the HW trust certificate. The NFVI exchanges user data responsive to the NFV MANO data when the HW trust certificate is valid. The NFVI isolates the NFV MANO data when the HW trust certificate is not valid.