Systems and methods related to processing transaction verification operations in decentralized applications via a fixed pipeline hardware architecture are described herein. The fixed pipeline hardware architecture may include and/or support at least a crypto engine and a read set validation engine. The crypto engine may itself comprise a hardware architecture configured to perform cryptographic operations necessary to validate signatures for transactions in decentralized applications. In various implementations, the hardware architecture of a crypto engine may include a scheduler and a series of crypto execution units configured to operate in parallel. The read set validation engine may be configured to verify whether a transaction is valid based on a comparison of an incoming transaction state indicating transaction data for the transaction and a local state related to the transaction.