Invention Grant
- Patent Title: Texaphyrin-Pt(IV) conjugates and compositions for use in overcoming platinum resistance
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Application No.: US15317560Application Date: 2015-06-11
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Publication No.: US10406167B2Publication Date: 2019-09-10
- Inventor: Jonathan L. Sessler , Jonathan Arambula , Zahid H. Siddik , Gregory Thiabaud
- Applicant: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
- Applicant Address: US TX Austin
- Assignee: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
- Current Assignee: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
- Current Assignee Address: US TX Austin
- Agency: Parker Highlander PLLC
- International Application: PCT/US2015/035229 WO 20150611
- International Announcement: WO2015/191797 WO 20151217
- Main IPC: A61K31/555
- IPC: A61K31/555 ; A61K31/407 ; A61K31/4188 ; C07D487/22 ; C07D405/14 ; A61K49/08 ; A61K49/10 ; A61K47/60 ; A61K47/54 ; C07F15/00
Abstract:
The present disclosure relates platinum(IV) and texaphyrin linked conjugates and compositions comprising a texaphyrin and a platinum(IV) agent. The present disclosure also provides pharmaceutical compositions of the conjugates and compositions. Also, provided herein are methods of using the instant compounds in the treatment of cancer such as a platinum resistant cancer.
Public/Granted literature
- US20170246182A1 TEXAPHYRIN-PT(IV) CONJUGATES AND COMPOSITIONS FOR USE IN OVERCOMING PLATINUM RESISTANCE Public/Granted day:2017-08-31
Information query
