Invention Grant
- Patent Title: Cell-penetrating bacterial E3-ubiqitin-ligases for use in immunotherapy
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Application No.: US15022827Application Date: 2014-09-22
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Publication No.: US10406215B2Publication Date: 2019-09-10
- Inventor: Marie-Luise Lubos , Alexander Schmidt , Christian Rueter
- Applicant: Westfälische Wilhelms-Universität Münster
- Applicant Address: DE Muenster
- Assignee: WESTFÄLISCHE WILHELMS-UNIVERSITÄT MÜNSTER
- Current Assignee: WESTFÄLISCHE WILHELMS-UNIVERSITÄT MÜNSTER
- Current Assignee Address: DE Muenster
- Agency: Duane Morris LLP
- Priority: EP13185412 20130920
- International Application: PCT/EP2014/070142 WO 20140922
- International Announcement: WO2015/040215 WO 20150326
- Main IPC: A61K38/53
- IPC: A61K38/53 ; C07K14/25 ; C07K14/255 ; C12N9/00 ; A61K38/16
Abstract:
The present invention relates to cell-penetrating effector proteins of type III secretion system (T3SS)-containing bacteria of the genus Salmonella or Shigella and variants, fragments and immunomodulatory domains thereof, for use in immunotherapy. The present invention further relates to cell-penetrating effector proteins of type III secretion system (T3SS)-containing bacteria of the genus Salmonella or Shigella and variants, fragments and immunomodulatory domains thereof, for delivering cargo molecules into eukaryotic cells.
Public/Granted literature
- US20160206713A1 CELL-PENETRATING BACTERIAL E3-UBIQITIN-LIGASES FOR USE IN IMMUNOTHERAPY Public/Granted day:2016-07-21
Information query
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