Invention Grant
- Patent Title: Double-labeled probe for molecular imaging and use thereof
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Application No.: US14335055Application Date: 2014-07-18
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Publication No.: US10406246B2Publication Date: 2019-09-10
- Inventor: Matthias Eder , Klaus Kopka , Martin Schaefer , Ulrike Bauder-Wuest , Uwe Haberkorn
- Applicant: DEUTSCHES KREBSFORSCHUNGSZENTRUM
- Applicant Address: DE Heidelberg
- Assignee: Deutsches Kresbsforschungszentrum
- Current Assignee: Deutsches Kresbsforschungszentrum
- Current Assignee Address: DE Heidelberg
- Agency: Kilpatrick Townsend & Stockton LLP
- Main IPC: A61K51/00
- IPC: A61K51/00 ; A61M36/14 ; A61K49/00 ; C07D497/10 ; C07D311/90 ; C07D209/60 ; C07D209/18 ; C07D401/14 ; G01N33/58 ; G01N33/574 ; A61K51/04
Abstract:
The present invention relates to a compound or a pharmaceutically acceptable salt thereof having a chemical structure comprising: (A) at least one motif specifically binding to cell membranes of neoplastic cells; (B) at least one chelator moiety of radiometals; and (C) at least one dye moiety; wherein said compound has a molecular weight of not more than 5 kDa. Further, the invention refers to a method for producing such compound and to the in vivo and in vitro uses thereof.
Public/Granted literature
- US20150110715A1 Double-Labeled Probe for Molecular Imaging and Use Thereof Public/Granted day:2015-04-23
Information query
