Invention Grant
- Patent Title: Spiro-isoquinoline-1,4′-piperidine compounds having multimodal activity against pain
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Application No.: US15527909Application Date: 2015-11-20
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Publication No.: US10407428B2Publication Date: 2019-09-10
- Inventor: Carmen Almansa-Rosales , Monica Garcia Lopez , Ana-Maria Caamano-Moure
- Applicant: ESTEVE PHARMACEUTICALS, S.A.
- Applicant Address: ES Barcelona
- Assignee: ESTEVE PHARMACEUTICALS, S.A.
- Current Assignee: ESTEVE PHARMACEUTICALS, S.A.
- Current Assignee Address: ES Barcelona
- Agency: Hueschen and Sage
- Priority: EP14382465 20141121
- International Application: PCT/EP2015/002332 WO 20151120
- International Announcement: WO2016/078770 WO 20160526
- Main IPC: C07D471/10
- IPC: C07D471/10 ; A61K31/423 ; C07D471/20 ; A61P25/04
Abstract:
The present invention relates to spiro-isoquinoline-1,4′-piperidine compounds having dual pharmacological activity towards both the sigma (σ) receptor and the μ-opiod receptor, to processes of preparation of such compounds, to pharmaceutical compositions comprising them, and to their use in therapy, in particular for the treatment of pain.
Public/Granted literature
- US20180111935A1 SPIRO-ISOQUINOLINE-1,4'-PIPERIDINE COMPOUNDS HAVING MULTIMODAL ACTIVITY AGAINST PAIN Public/Granted day:2018-04-26
Information query
