Invention Grant
- Patent Title: Anti-MCAM antibodies and associated methods of use
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Application No.: US15125570Application Date: 2015-03-12
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Publication No.: US10407506B2Publication Date: 2019-09-10
- Inventor: Yue Liu
- Applicant: PROTHENA BIOSCIENCES LIMITED
- Applicant Address: IE Dublin
- Assignee: PROTHENA BIOSCIENCES LIMITED
- Current Assignee: PROTHENA BIOSCIENCES LIMITED
- Current Assignee Address: IE Dublin
- Agency: Alston & Bird LLP
- International Application: PCT/IB2015/051786 WO 20150312
- International Announcement: WO2015/136469 WO 20150917
- Main IPC: C07K16/00
- IPC: C07K16/00 ; C07K16/30 ; C12P21/00 ; G01N33/577 ; G01N33/68
Abstract:
The invention provides anti-MCAM antibodies that inhibit the ability of human MCAM to bind a laminin alpha-4 chain. The invention also provides pharmaceutical compositions, methods of generating such antibodies, and their use in the manufacture of medicaments for treatment of neuroinflammatory disease, autoimmune disease, or cancer.
Public/Granted literature
- US20170002089A1 ANTI-MCAM ANTIBODIES AND ASSOCIATED METHODS OF USE Public/Granted day:2017-01-05
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