Provided are a protection circuit for a brushless DC motor, and a control device. The protection circuit is applied to a control device for a brushless DC motor, the control device including a main control chip and a protection circuit for driving a brushless DC motor. The protection circuit includes a sampling signal input end (RNF), a first resistor (R1), a first capacitor (C1), a second capacitor (C2), a comparator (IC2) and a switching element (IC1), connected together in a preset structure.