A voltage detection circuit is disclosed. The voltage detection circuit includes a threshold voltage detection circuit, a current leakage compensation circuit and a low voltage detection circuit. The threshold voltage detection circuit detects the voltage of a power source and determines whether the voltage is dropped over a threshold voltage, so as to wake up the low voltage detection circuit. The current leakage compensation circuit determines whether a voltage difference between the first voltage and the second voltage exceeds a preset value, so as to generate a trigger signal to activate the low voltage detection circuit. As a result, the voltage detection circuit can have high efficiency and low power consumption, and can detect the voltage drop more accurately in environment with current leakage, temperature variation, or process variation.