Provided herein is an image processing method and device for a Light Emitting Diode (LED) display screen. The image processing method for an LED display screen includes: receiving original image data; acquiring information of an original pixel according to the original image data; executing the information of the original pixel computation according to a preset algorithm to obtain information of target pixels; and controlling an image corresponding to the original image data according to the color information of the target pixel and the position information of the target pixel to be displayed on the LED display screen panel. The disclosure improves the quality of a displayed image of an LED display screen.