Invention Grant
- Patent Title: Compounds for inducing anti-tumor immunity and methods thereof
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Application No.: US15877864Application Date: 2018-01-23
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Publication No.: US10421965B2Publication Date: 2019-09-24
- Inventor: Juan R. Cubillos-Ruiz , Laurie H. Glimcher
- Applicant: Cornell University
- Applicant Address: US NY Ithaca
- Assignee: Cornell University
- Current Assignee: Cornell University
- Current Assignee Address: US NY Ithaca
- Agency: Schwegman Lundberg & Woessner, P.A.
- Main IPC: C07H21/04
- IPC: C07H21/04 ; C12N15/113 ; A61K31/713 ; A61K45/06
Abstract:
Described herein is a previously unknown function of XBP1 in controlling anti-tumor immunity. It is shown that inhibiting XBP1 in tumor-associated dendritic cells inhibits tumor growth and induces protective anti-tumor immune responses.
Public/Granted literature
- US20180258426A1 COMPOUNDS FOR INDUCING ANTI-TUMOR IMMUNITY AND METHODS THEREOF Public/Granted day:2018-09-13
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