An aging test system and method are disclosed. An aging test system includes a vacuum chamber provided with an aging device for aging a display panel; a lighting mechanism electrically connected to the display panel for lighting up the display panel; at least one spectrometer for detecting a color coordinate and a brightness of the display panel; at least one camera for detecting a dark spot defect of sub-pixels of the display panel. Accordingly, the present invention can save the inspection time, increase the inspection efficiency and save the inspection device in order to reduce the inspection cost.