Invention Grant
- Patent Title: Human anti TSHR antibodies
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Application No.: US14790489Application Date: 2015-07-02
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Publication No.: US10428153B2Publication Date: 2019-10-01
- Inventor: Bernard Rees-Smith , Jane Sanders , Jadwiga Furmaniak
- Applicant: RSR Ltd.
- Applicant Address: GB Lancaster
- Assignee: RSR Ltd.
- Current Assignee: RSR Ltd.
- Current Assignee Address: GB Lancaster
- Agency: Fish & Richardson P.C.
- Priority: GB0823562.4 20081224; GB0908945.9 20090522
- Main IPC: A61K39/00
- IPC: A61K39/00 ; C07K16/28
Abstract:
According to one aspect there is provided An isolated human antibody molecule which binds to the TSHR and which reduces ligand-induced stimulation of the TSHR but has no effect on TSHR constitutive activity wherein the isolated human antibody molecule has the characteristic of patient serum TSHR autoantibodies of inhibiting TSH and M22 binding to the TSHR.
Public/Granted literature
- US20150344582A1 HUMAN ANTI TSHR ANTIBODIES Public/Granted day:2015-12-03
Information query
