Invention Grant
- Patent Title: Restoration of the CFTR function by splicing modulation
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Application No.: US14667285Application Date: 2015-03-24
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Publication No.: US10428328B2Publication Date: 2019-10-01
- Inventor: Batsheva Kerem , Michal Tur Sinai , Loren Price , Stephen Donald Wilton , Sue Fletcher
- Applicant: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
- Applicant Address: IL Jerusalem
- Assignee: YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD.
- Current Assignee: YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD.
- Current Assignee Address: IL Jerusalem
- Agency: The Roy Gross Law Firm, LLC
- Agent Roy Gross
- Main IPC: C12N15/11
- IPC: C12N15/11 ; C12N15/113 ; A61K48/00 ; C07H21/02 ; C07H21/04 ; A61K31/7105 ; A61K45/06
Abstract:
Oligonucleotides capable of binding to and modulating the splicing of the pre-mRNA of the CFTR gene, compositions including the oligonucleotides, kits including the compositions, and uses thereof. Compositions of oligonucleotides useful in methods for suppressing exon 10 skipping optionally in combination with additional CFTR therapeutics.
Public/Granted literature
- US20150211010A1 Restoration Of The CFTR Function By Splicing Modulation Public/Granted day:2015-07-30
Information query
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