Invention Grant
- Patent Title: Genetically encoded potassium ion indicators
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Application No.: US15975427Application Date: 2018-05-09
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Publication No.: US10429374B2Publication Date: 2019-10-01
- Inventor: Emrah Eroglu , Helmut Bischof , Wolfgang Graier , Roland Malli , Markus Waldeck-Weiermair
- Applicant: Medizinische Universität Graz
- Applicant Address: AT Braz
- Assignee: MEDIZINISCHE UNIVERSITÄT GRAZ
- Current Assignee: MEDIZINISCHE UNIVERSITÄT GRAZ
- Current Assignee Address: AT Braz
- Agency: Pepper Hamilton LLP
- Priority: ATA50400/2017 20170511
- Main IPC: G01N33/52
- IPC: G01N33/52 ; G01N33/487 ; C12N15/63 ; C07K14/00 ; G01N33/50 ; G01N33/49 ; G01N33/542 ; G01N33/84
Abstract:
The present invention relates to a polypeptide comprising at least one signaling domain and a potassium sensor which is capable of binding K+ and the first signaling domain is capable of generating a detectable signal upon binding of K+ to the potassium sensor. The invention also relates to a polynucleotide encoding said polypeptide and the use of the polypeptide in various applications for the detection of K+.
Public/Granted literature
- US20180328908A1 GENETICALLY ENCODED POTASSIUM ION INDICATORS Public/Granted day:2018-11-15
Information query
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