A GPU may be configured to detect and nullify unnecessary instructions. Nullifying unnecessary instructions include overwriting a detected unnecessary instruction with a no operation (NOP) instruction. In another example, nullifying unnecessary instructions may include writing a value to a 1-bit instruction memory. Each bit of the 1-bit instruction memory may be associated with a particular instruction of the draw call. If the 1-bit instruction memory has a true value (e.g., 1), the GPU is configured to not execute the particular instruction.