This disclosure describes an enhanced temperature validation slide comprising a substrate and a removable label attached to the substrate with an adhesive. In some implementations, the label comprises at least two threshold temperature indicators, a transparent liquid impermeable barrier layer, a designated area for user generated information, an area for displayed information (i.e. a lot number), an area for displayed text or graphics linked to information stored online (i.e. a QR code), and a thermo-chromic visual indicator area. The various implementations of this disclosure may describe a validation slide utilizing any number of the features described above in any combination.