System, method, and computer program product for evaluating attribute values to determine treatment eligibility, the method by receiving a set of required attributes associated with a treatment protocol, receiving a case, wherein the case includes a patient history containing patient attribute values, identifying a patient attribute value that does not satisfy a required attribute specified by the treatment protocol, determining a likelihood that the patient could meet the required attribute based upon the patient history, and providing an indication of the likelihood that the patient could satisfy the required attribute specified by the treatment protocol.