Systems and methods are provided for detection and compensation of frequency drifts. Frequency related information may be determined for each of one or more channels in an input signal, and a frequency drift may be determined based on the determined frequency related information of the one or more channels. Frequency related adjustments may be determined based on the frequency drift, and the frequency related adjustments may be applied to different circuits used during one or more of: receiving of the input signal, processing of the input signal, processing of an intermediate signal generated based on the processing of the input signal, and generating of an output signal corresponding to the input signal. Applying the frequency related adjustments may be configured to meet one or more criteria.