The present invention relates to a midsole for dispersing the pressure of the mesopodium and the metatarsal bones, and a shoe having the same, the midsole having, installed in a metatarsal bone portion and mesopodium portion of the central upper part thereof, a midfoot support for receiving an inner sole, which protrudes upwardly so as to support the mesopodium, and having a bridge groove formed in a metatarsal bone portion of the lower part thereof, wherein the bridge groove consists of three components, and has been improved so as to be capable of supporting joints between the metatarsal bone body and basal tarsus metatarsal bones.