A shaker bottle having a vessel for retaining a liquid volume, a lid for closing said vessel, a container for storing a powder supplement, and an accessory compartment for storing valuables. The container is releasably arranged to a lower surface of the lid. The vessel is foldable for providing a folded state of the shaker bottle during transportation. The container is received by the bottom of the vessel in the folded state, and thus the release of the container is locked. In an unfolded state the container is released for supply of the powder supplement to the liquid in the vessel, while the container is serving as a stirring device. A method for use of the shaker bottle is provided for securing a safe storing of powder supplements during transportation and for improving the functionality of a shaker bottle for every user with an active lifestyle.