Invention Grant
- Patent Title: Oxysterol-statin compounds for bone growth
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Application No.: US15599577Application Date: 2017-05-19
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Publication No.: US10434106B2Publication Date: 2019-10-08
- Inventor: Steven M. Peckham , Roger E. Harrington , Jerbrena C. Jacobs
- Applicant: Warsaw Orthopedic, Inc.
- Applicant Address: US IN Warsaw
- Assignee: WARSAW ORTHOPEDIC, INC.
- Current Assignee: WARSAW ORTHOPEDIC, INC.
- Current Assignee Address: US IN Warsaw
- Main IPC: A61K31/575
- IPC: A61K31/575 ; A61K35/32 ; A61K38/18 ; A61K45/06 ; C07J7/00 ; C07J9/00 ; C07J17/00 ; C07J43/00 ; C07J51/00
Abstract:
Oxysterol-statin compounds and methods of synthesizing the same are provided for use in promoting osteogenesis, osteoinduction andior osteoconduction. Methods of synthesizing in a single container OXY133-statin compounds having high yields and improved process safety are also provided. Methods for synthesizing OXY133-statin compounds that are stereoselective are also provided. Methods of synthesizing OXY133-statin conjugates that have low production costs are provided.
Public/Granted literature
- US20180333424A1 OXYSTEROL-STATIN COMPOUNDS FOR BONE GROWTH Public/Granted day:2018-11-22
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