Invention Grant
- Patent Title: Positive allosteric modulators of muscarinic M2 receptor
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Application No.: US15735138Application Date: 2016-06-06
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Publication No.: US10435403B2Publication Date: 2019-10-08
- Inventor: Henrik Teller , Alexander Straub , Markus Brechmann , Thomas Müller , Mark Meininghaus , Katrin Nowak-Reppel , Hanna Tinel , Klaus Münter , Daniela Fliegner , Thomas Mondritzki , Melissa Boultadakis Arapinis , Tobias Marquardt , Alexandros Vakalopoulos , Anne-Sophie Rebstock , Matthias Beat Wittwer
- Applicant: Bayer Pharma Aktiengesellschaft
- Applicant Address: DE Berlin
- Assignee: Bayer Pharma Aktiengesellschaft
- Current Assignee: Bayer Pharma Aktiengesellschaft
- Current Assignee Address: DE Berlin
- Agency: Morrison & Foerster LLP
- Priority: EP15171127 20150609; EP16156676 20160222
- International Application: PCT/EP2016/062737 WO 20160606
- International Announcement: WO2016/198342 WO 20161215
- Main IPC: C07D471/04
- IPC: C07D471/04 ; A61P9/04 ; A61K31/4375 ; A61K31/4545 ; A61K31/496 ; A61K31/513 ; A61K31/5377 ; A61K45/06 ; C07D519/00

Abstract:
The present application relates to positive allosteric modulators of the muscarinic M2 receptor, especially to novel 7-substituted 1-arylnaphthyridine-3-carboxamides, to processes for preparation thereof, to the use thereof, alone or in combinations, for treatment and/or prevention of diseases, and to the use thereof for production of medicaments for treatment and/or prevention of diseases, in particular for treatment and/or prevention of cardiovascular disorders and/or renal disorders.
Public/Granted literature
- US20180297994A1 POSITIVE ALLOSTERIC MODULATORS OF MUSCARINIC M2 RECEPTOR Public/Granted day:2018-10-18
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