At least one example embodiment relates to a thermoresponsive smart adhesive pad. Provided is a thermoresponsive smart adhesive pad that includes a polymer layer including a plurality of concave grooves; a hydrophilic surface layer formed on the polymer layer; and a coating layer including a hydrogel and formed on the hydrophilic surface layer. Also, provided is a method of manufacturing a thermoresponsive smart adhesive pad, including forming a plurality of convex structures on a substrate; forming a plurality of concave grooves in a polymer layer using the substrate on which the plurality of convex structures are formed; forming a hydrophilic surface layer by performing a hydrophilic treatment of a surface of the polymer layer in which the plurality of concave grooves are formed; forming, on the hydrophilic surface layer, a coating layer including a mixed solution containing a hydrogel monomer; and irradiating ultraviolet (UV) rays to the coating layer.