Invention Grant
- Patent Title: Method of co-expressing a glycoprotein and a single-subunit olicosaccharyltransferase in a plant
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Application No.: US14895350Application Date: 2014-06-03
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Publication No.: US10435704B2Publication Date: 2019-10-08
- Inventor: Franziska Jarczowski , Romy Kandzia , Frank Thieme , Victor Klimyuk , Yuri Gleba
- Applicant: Icon Genetics GmbH
- Applicant Address: DE München
- Assignee: Icon Genetics GmbH
- Current Assignee: Icon Genetics GmbH
- Current Assignee Address: DE München
- Agent David M. Saravitz; Williams Mullen
- Priority: EP13002866 20130604
- International Application: PCT/EP2014/001500 WO 20140603
- International Announcement: WO2014/195011 WO 20141211
- Main IPC: C12N15/82
- IPC: C12N15/82 ; C07K16/28 ; C07K16/32 ; C12N9/10

Abstract:
A process of producing a recombinant glycoprotein in a plant, in cells of a plant, or in plant cells is provided. The process comprises expressing in said plant, in cells of said plant or in said plant cells a nucleic acid sequence encoding a polypeptide having an N-glycosylation site and co-expressing a nucleic acid sequence encoding a heterologous single-subunit oligosaccharyltransferase.
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