Invention Grant
- Patent Title: Methods for detecting colorectal cancer using a DNA marker of exfoliated epithelia and a fecal blood marker
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Application No.: US14954496Application Date: 2015-11-30
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Publication No.: US10435753B2Publication Date: 2019-10-08
- Inventor: Hongzhi Zou , David Ahlquist , Jonathan J. Harrington
- Applicant: Mayo Foundation for Medical Education and Research
- Applicant Address: US MN Rochester
- Assignee: Mayo Foundation for Medical Education and Research
- Current Assignee: Mayo Foundation for Medical Education and Research
- Current Assignee Address: US MN Rochester
- Agency: Casimir Jones, SC
- Agent Robert A. Goetz
- Main IPC: C12Q1/6886
- IPC: C12Q1/6886 ; G01N33/574

Abstract:
The present invention provides methods and materials related to the detection of colorectal neoplasm-specific markers in or associated with a subject's stool sample. In particular, the present invention provides methods and materials for identifying mammals having a colorectal neoplasm by detecting the presence of exfoliated epithelial markers (e.g., human DNA, tumor assoicated gene alterations, tumor associated proteins) and blood markers (e.g., homoglobin, serum proteins) in a stool sample obtained from the mammal.
Public/Granted literature
- US20160083803A1 METHODS AND MATERIALS FOR DETECTING COLORECTAL NEOPLASM Public/Granted day:2016-03-24
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