A device for detecting concave-convex of a flange face of a wheel is composed of a frame, a jacking cylinder, lower guide posts, a lifting table, a support column, a first inner ring adjusting cylinder, an inner ring guide rail, an second inner ring adjusting cylinder, a first inner ring sliding block, a second inner ring sliding block, a first electric cylinder, a second electric cylinder, a first detection bar, a second detection bar, piezoelectric sensors, a first outer ring adjusting cylinder, a second outer ring adjusting cylinder, a first outer ring guide rail, a second outer ring guide rail, a first outer ring sliding block, a second outer ring sliding block, a third electric cylinder, a fourth electric cylinder, a third detection bar, a fourth detection bar and the like.