Invention Grant
- Patent Title: Portable fluorescence detection system and microassay cartridge
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Application No.: US15804869Application Date: 2017-11-06
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Publication No.: US10436713B2Publication Date: 2019-10-08
- Inventor: C. Frederick Battrell , Troy D. Daiber , William Samuel Hunter
- Applicant: Micronics, Inc.
- Applicant Address: US WA Redmond
- Assignee: MICRONICS, INC.
- Current Assignee: MICRONICS, INC.
- Current Assignee Address: US WA Redmond
- Agency: Seed IP Law Group LLP
- Main IPC: G01N21/64
- IPC: G01N21/64 ; B01L3/00 ; B01L7/00

Abstract:
A compact, microprocessor-controlled instrument for fluorometric assays in liquid samples has a floating stage with docking bay for receiving a microfluidic cartridge and a scanning detector head with on-board embedded microprocessor controlled by an optical data acquisition and processing daemon within the detector head for controlling source LEDs, emission signal amplification and filtering in an isolated, low noise, high-gain environment within the detector head. Multiple optical channels may be incorporated in the scanning head. The assay ma be validated using dual channel optics for monitoring a first fluorophore associated with a target analyte and a second fluorophore associated with a control. Molecular biological assays use PCR amplification of target nucleic acids and fluorometric assays, which may require temperature control during detection. Sensitivity and resistance to bubble interference during scanning are improved using a heating block with reflective mirror face in contact with a thermo-optical window enclosing the liquid sample.
Public/Granted literature
- US20180292319A1 PORTABLE FLUORESCENCE DETECTION SYSTEM AND MICROASSAY CARTRIDGE Public/Granted day:2018-10-11
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