A control system and a control method of manufacturing injection molding products are provided. The control system includes an injection molding machine, an information input interface, a computing server and a data conversion device. At first, product information is inputted through the information input interface. The product information is transmitted to the computing server, and then the computing server determines injection molding parameters according to the product information. The injection molding parameters are transmitted to the information input interface. After data conversion through the data conversion device, the injection molding machine is controlled to manufacture the injection molding products according to the converted injection molding parameters.