Systems and methods of mitigating signal interference in communications involving an antenna array can include determining a radiation pattern of the antenna array in communication with a first communication device. The method can include determining that a power level or gain of the antenna array in a direction pointing to a second communication device exceeds a predefined threshold value, using the radiation pattern of the antenna array and a position of the second communication device. The method can include identifying one or more antenna elements among a plurality of antenna elements of the antenna array to be powered off or applying non-uniform weighting to the antenna elements to distort the radiation pattern of the antenna array in a way to reduce the power level or gain of the antenna array in the direction pointing to the second communication device.