An interface conversion circuit, a display panel driving method and a display apparatus for realizing UHD image display at least by a LVDS interface together with an UHD display apparatus are provided. The interface conversion circuit comprises a low voltage differential signaling (LVDS) interface and a data format conversion module. The LVDS interface is configured to receive a LVDS signal from a LVDS signal source and transmit the LVDS signal to the data format conversion module. The data format conversion module is configured to convert the received LVDS signal into a digital video interface eDP signal.