Technologies for dynamically allocating tiers of disaggregated memory resources include a compute device. The compute device is to obtain target performance data, determine, as a function of target performance data, memory tier allocation data indicative of an allocation of disaggregated memory sleds to tiers of performance, in which one memory sled of one tier is to act as a cache for another memory sled of a subsequent tier, send the memory tier allocation data and the target performance data to the corresponding memory sleds through a network, receive performance notification data from one of the memory sleds in the tiers, and determine, in response to receipt of the performance notification data, an adjustment to the memory tier allocation data.