Methods, devices, controllers and systems for color calibration of displays, non-volatile (non-transient) memory, controllers, display devices or display systems including a color calibration transform, operation of such controllers, display devices or systems and software for color calibration of a display are described are described that make use of a color transform having a distribution of color points across a full display gamut (hence optionally preserving full contrast and color saturation in the calibrated display) in an at least substantially perceptually uniform manner suitable for use as a color display calibration adapted for medical applications. A perceptually uniform spread of color points can be in terms of a distance metric such as deltaE2000 for color or JND for gray.