A nonaqueous electrolyte secondary battery includes a positive electrode, a negative electrode, a separator provided between the positive electrode and the negative electrode, and a nonaqueous electrolytic solution at least held by the separator. The positive electrode has a positive electrode collector and a positive electrode mixture layer provided on the positive electrode collector. The positive electrode mixture layer has a first powder and a second powder. The first powder includes a first positive electrode active material, a first conductive material, and an organic-based binder. The second powder includes a second positive electrode active material, a second conductive material, and a water-based binder.