Individualized connectivity based request handling is disclosed. For example, a content source is accessed by a client device and a load balancer executes on a processor to receive a first request based on the client device accessing the content source. A first session variable is set to a first value in a first session and a first latency to the client device is measured. A first plurality of target nodes is selected based on the first session variable. A first plurality of messages is sent to the first plurality of target nodes. A second request is received from the client device after the first session expires, starting a second session. The first session variable is set to a different second value in the second session. A second plurality of messages is sent to a second plurality of target nodes different from the first plurality of target nodes.