Methods and systems are provided for matrixed audio settings. In an audio system that comprises at least one audio output element operable to output audio signals, a first user input that comprises a selection of audio mode may be received, and based on the selected audio mode, one or more audio settings applicable during generating, processing, and/or outputting of the audio signals may be determined. At least one user control element may be configured to enable receiving of a second user input that comprises a selection between the determined one or more corresponding audio settings. The audio system (or at least the audio output element thereof) may be a headset.