Systems and method of reducing interference in a wireless communication system are provided. In one exemplary embodiment, a method by a wireless device (105, 200, 300a, 300b, 500, 1105, 1205, 1207) comprises determining (409, 909) an uplink precoder (107) based on channel measurements on first and second downlink reference signal resources. Further, the precoder enables a transmission (113) on an uplink reference signal resource that is precoded with the uplink precoder and that is quasi co-located (QCL) (121) with a transmission (111) on the first downlink reference signal resource but not QCL (123) with a transmission (115) on the second downlink reference signal resource.