Invention Grant
- Patent Title: Molecules that inhibit efflux pumps in multi-drug resistant bacteria and uses thereof
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Application No.: US15186070Application Date: 2016-06-17
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Publication No.: US10463044B2Publication Date: 2019-11-05
- Inventor: George W. Gokel , Michael R. Gokel , Saeedeh Negin , Mohit B. Patel
- Applicant: The Curators of the University of Missouri
- Agency: Thompson Coburn LLP
- Agent William A. Holtz
- Main IPC: A01N43/72
- IPC: A01N43/72 ; A61K45/06 ; A61K31/165 ; A61K31/395 ; A61K31/496 ; A61K31/65 ; A61K38/16
Abstract:
Methods and compositions are provided for increasing or enhancing the efficacy of antibiotics, such as by increasing antimicrobial activity, against a variety of microbes by co-administration with synthetic amphiphiles, including lariat ethers and hydraphiles. Methods and compositions for overcoming antibiotic resistance are also provided.
Public/Granted literature
- US20160361292A1 Molecules That Inhibit Efflux Pumps in Multi-Drug Resistant Bacteria and Uses Thereof Public/Granted day:2016-12-15
Information query
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