Invention Grant
- Patent Title: Interaction of methylated LSD1 and CHD1, a compound inhibiting this interaction for use in therapy, and a screening method for such a compound
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Application No.: US15554169Application Date: 2016-02-24
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Publication No.: US10463630B2Publication Date: 2019-11-05
- Inventor: Eric Metzger , Roland Schüle
- Applicant: Albert-Ludwigs-Universität Freiburg
- Applicant Address: DE Freiburg
- Assignee: Albert-Ludwigs-Universität Freiurg
- Current Assignee: Albert-Ludwigs-Universität Freiurg
- Current Assignee Address: DE Freiburg
- Agency: Leydig, Voit & Mayer, Ltd.
- Priority: GB1503339.2 20150227
- International Application: PCT/EP2016/053808 WO 20160224
- International Announcement: WO2016/135165 WO 20160901
- Main IPC: A61K31/00
- IPC: A61K31/00 ; G01N33/68
Abstract:
Disclosed in the present application are: (i) a compound inhibiting the interaction between LSD1me2 and CHD1 for use in therapy, (ii) a compound inhibiting the interaction between LSD1me2 and CHD1 for use in treating cancer, in particular prostate cancer, and (iii) a method of screening for such a compound.
Public/Granted literature
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